• br is a bacterial infection

  2019-06-28

  

  is a bacterial infection causing necrotising lesions of skin and subcutaneous tissue. Widely known as Buruli ulcer, it is classified as a neglected tropical disease by WHO. If diagnosed and treated early, outcomes are good, but if left untreated it can progress to a severe disease resulting in hig

• br In its July editorial drew attention to the

  2019-06-28

  

  In its July editorial, drew attention to the ethical challenges posed by the Zika Loxapine outbreak. The Regional Program on Bioethics at the Pan American Health Organization (PAHO) arranged an ethics consultation, funded by the Wellcome Trust, to provide ethically sound guidance for the outbreak.

• br Discussion Variant angina was

  2019-06-28

  

  Discussion Variant Maprotiline HCl was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such cases [2,3]. Coron

• br Conflict of interest br Introduction Idiopathic left vent

  2019-06-28

  

  Conflict of interest Introduction Idiopathic left ventricular tachycardia (ILVT) with a right bundle-branch block (RBBB) configuration and superior or left axis is a distinct entity that arises in the left ventricle, mostly because of a reentry mechanism and is usually verapamil sensitive [1–6

• br Commentary The concept of entrainment mapping for

  2019-06-28

  

  Commentary The concept of entrainment mapping for ablation of VT is that targeting the site will interrupt the reentrant VT circuit. This site must be located, not only within the circuit, but also in a protected and relatively narrow isthmus. During entrainment mapping, the QRS morphology, S-QRS

• br Case report A year

  2019-06-28

  

  Case report A 58-year-old woman presented to our hospital with a history of several weeks of chronic dry cough and intermittent shortness of breath. On physical examination, the patient\'s blood pressure was 135/85 mmHg, oral temperature was 37.4 °C, pulse rate was 112/min, and her respiratory ra

• Editorial opinion piece Many patients

  2019-06-28

  

  Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect

• br The role of P in tumors br The role

  2019-06-28

  

  The role of P62 in tumors The role of P62 in osteoclastogenesis P62 as an oncotarget for treatment Concluding remarks P62 is a cellular “Swiss army knife,” with its diverse cellular functions arising from its unique functional motifs and protein–protein interaction properties. P62 may pl

• br Conclusion br Conflict of

  2019-06-28

  

  Conclusion Conflict of interest Introduction Giant cell tumor (GCT) is a primary intramedullary bone tumor that is composed of mononuclear and giant mononuclear cells, resembling MK-5172 [1]. It usually involves the end of a long bone. The World Health Organization has classified GCT as an

• Preamble The J wave syndromes

  2019-06-28

  

  Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology Pyridone 6 over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [1

• M s all de la tiran

  2019-06-28

  

  Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto Sorbitol la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción poética de Neruda: la

• Autophagy can be generally divided into non selective bulk a

  2019-06-28

  

  Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein RGDfK u

• Introduction Cancer therapy has evolved throughout the decad

  2019-06-27

  

  Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of

• Vardenafil HCl Trihydrate After CRT D implantation the

  2019-06-27

  

  After CRT-D implantation, the QRS duration decreased to 122ms (Fig. 2), and the cardiac dyssynchrony improved. However, 5 days after implantation, atrial flutter (AFL) and electrical storm presenting as frequent VT were seen. As shown in Fig. 3A, the VT was initiated by a premature ventricular compl

• Complete resection of the tumor with negative

  2019-06-27

  

  Complete resection of the tumor with negative margins at the time of diagnosis appears the most preferred mode of intervention towards favorable prognosis. It is worth mentioning that the germline NU 9056 structure of DICER1 is believed as the genetic cause in the majority of PPB; consequently, ear

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