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In response to the lack
2019-05-13

In response to the lack of epidemiological information on typhoid in Africa, the Typhoid Fever Surveillance in Africa Programme (TSAP), funded by the Bill & Melinda Gates Foundation and covering ten countries and 13 sites across Africa, was established between 2010 and 2014. In this Merimepodib manu
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br Material and methods br Results br Discussion ES SCLC
2019-05-13

Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of
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Development of an atrial esophageal fistula is one of
2019-05-13

Development of an atrial–esophageal fistula is one of the most dreaded complications of AF ablation [78]. A relatively large-scale nonrandomized study revealed that the anatomical risk factor of a small LA-to-esophageal distance was the most important factor in esophageal ulceration when using an ir
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br Case report A year old female presented with
2019-05-13

Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (1st school functioning of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin
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Therefore the patient was diagnosed with BIP and steroid
2019-05-13

Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th
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The following is the Supplementary
2019-05-13

The following is the Supplementary material related to this article Video 1, Video 2, Video 3. Discussion In the electrophysiology setting, increased pericardial effusion or tamponade risk is associated with left-sided arrhythmia ablations, biventricular pacemaker placements, and implantable car
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br Results br Discussion We
2019-05-13

Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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br Acknowledgements br Introduction The
2019-05-13

Acknowledgements Introduction The chronic myeloproliferative neoplasms (MPN) comprise a group of clonal stem cell disorders with a high prevalence of the JAK2 V617F mutation (JAK2+) causing excessive production of mature blood cells. Transformation to acute myeloid leukemia (AML) is seen in 2–
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With the availability of vaccines
2019-05-13

With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th
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br Entrainment As the principles of entrainment
2019-05-13

Entrainment As the principles of entrainment initially described by Waldo for atrial flutter could be fulfilled by scar-mediated VT, characterization of the reentrant circuit provided a central isthmus as a favorable target [33,34]. In the late 1980s, the collective descriptions of entrainment, o
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The pre procedural venogram showed total occlusion of
2019-05-13

The pre-procedural venogram showed total occlusion of the left BCV and the formation of an acute angle between the right BCV and SVC caused by tuberculosis-induced lung destruction (Fig. 1A and B). We adopted a right-sided venous approach via the right subclavian vein (SCV) for a single chamber. Ini
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Apart from their association with severe
2019-05-10

Apart from their association with severe pain and reduced quality of life, SREs require substantial healthcare resource utilization (HRU) in their treatment and management. Previous retrospective studies have attempted to quantify various aspects of the burden of SREs across specific tumor types/co
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Ablation of a left sided accessory pathway requires
2019-05-10

Ablation of a left-sided accessory pathway requires delivery of RF current to the tissue near the mitral valve annular ring. These lesions may potentially cause mitral injury. Sometimes a trapped leaflet or chordae underneath the tip of the catheter may cause the insufficiency [7,8,12–14]. However,
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At least genes are associated with
2019-05-10

At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva
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equol br Es curioso observar que en el terreno
2019-05-10

Es curioso observar que en el terreno de la crítica musical, la tarea fundamental es evidentemente depurar la teoría de todo aquello que obstaculiza la formulación precisa de los elementos esenciales de la música. Sin embargo, cuando se trata de estudiar el tema de la música en la literatura, nada
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